Package: glyenzy
Title: Deconstruction Glycosylation Biosynthesis
Version: 0.10.0
Authors@R: 
    person("Bin", "Fu", , "23110220018@m.fudan.edu.cn", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0001-8567-2997"))
Description: Simulates the biosynthetic process of glycosylation in
        silico, enabling computational analysis of glycan biosynthesis
        pathways. Key features include: identifying specific
        glycosyltransferases responsible for each glycosidic bond at
        the bond level; reconstructing complete biosynthetic pathways
        for given glycans; exploring possible transformations between
        two glycan structures via glycosyltransferases, glycosidases,
        and sulfotransferases; and predicting glycans that can be
        synthesized from substrate structures and enzyme sets. The
        package supports multiple glycan types including N-glycans,
        O-GalNAc, O-Man, O-GlcNAc, O-Fuc, and O-Glc, selected
        glycosphingolipid headgroups, and sulfate modifications in
        canonical N- and O-glycan contexts. Lipid aglycones are not
        represented, so glycolipid rules model their carbohydrate
        headgroups with ceramide omitted. As a downstream component of
        the glycoverse ecosystem, it integrates seamlessly with
        'glyrepr', 'glyparse', and 'glymotif' to provide practical,
        analysis-ready insights into glycan biosynthesis for omics
        researchers.
License: MIT + file LICENSE
Suggests: ggraph, knitr, rmarkdown, testthat (>= 3.0.0), withr
Config/testthat/edition: 3
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
URL: https://glycoverse.github.io/glyenzy/
LinkingTo: Rcpp, BH
SystemRequirements: C++17
Imports: Rcpp, checkmate, cli, glydraw (>= 0.8.0), glyexp (>= 0.15.0),
        glymotif (>= 0.19.0), glyrepr (>= 1.0.0), glyparse (>= 0.5.3),
        igraph, purrr, fastmap, dplyr, rlang, tibble, R6, ggplot2,
        S4Vectors, SummarizedExperiment
Depends: R (>= 4.1)
VignetteBuilder: knitr
Config/roxygen2/version: 8.0.0
RoxygenNote: 7.3.3
Config/pak/sysreqs: cmake libglpk-dev make libicu-dev libpng-dev
        libuv1-dev libxml2-dev zlib1g-dev
Repository: https://glycoverse.r-universe.dev
Date/Publication: 2026-10-08 13:58:12 UTC
RemoteUrl: https://github.com/glycoverse/glyenzy
RemoteRef: v0.10.0
RemoteSha: 953ae7ac50792f7a4d8d63508531ca18049d5628
NeedsCompilation: yes
Packaged: 2026-10-22 05:40:02 UTC; root
Author: Bin Fu [aut, cre] (ORCID: <https://orcid.org/0000-0001-8567-2997>)
Maintainer: Bin Fu <23110220018@m.fudan.edu.cn>